Tools and Methods

The PHAGO project will develop a number of in vitro and in vivo models to investigate the role of TREM2 and CD33 in neuroinflammation and Alzheimer’s disease. Wherever possible, tools and methods will be shared with the wider research community.

 

 

EBiSC - Global supplier of iPSC lines

iPSC lines generated in the PHAGO project

All generated iPSC lines within the PHAGO project are and will be deposited in the iPSC line catalogue where they are available to the research community.

 

Generated iPSC lines are:

 

iPSC line EBiSC identifier
CD33 KO BIONi10-C-9
CD33 ΔExon2 BIONi10-C-5
TREM2 KO BIONi10-C-17
TREM2 R47H BIONi10-C-7
TREM2 T66M BIONi10-C-8

 

 

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This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115976. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA companies.

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This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115976. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA companies.